Analysis Notebooks

• Ascertaining the generalisability of the structure data
• Centre of mass analysis
• Compare D-scores
• Comparing apo and holo CDR loop clustering
• Comparison of apo and holo CDR loops
• Identify contact residues on MHC Class I molecules
• Length dependency of conformational change
• Modalities of TCR interactions with pMHCs
• Per residue changes of TCR CDRs between apo and holo structures
• Summary of apo-holo data
• Visualising CDR loop clustering
• pMHC movement based on peptide anchoring
• pMHC movement between apo and holo conformations